教育经历
2010/09-2014/07，河南师范大学，生命科学学院，本科
2014/09-2017/07，河南师范大学，生命科学学院，硕士
2017/08-2020/06，新奥门31999，新奥门31999，博士
主持项目
1. 中国博士后科学基金会, 中国博士后科学基金第69批面上资助, 2021M693678 （主持）；
2. 广东省基础与应用基础研究基金项目——青年基金项目，2021A1515110204（主持）。
发表论文
Zhang WW, Weng J, Yao L, Jia P, Yi M, Jia K. Nectin4 antagonises type I interferon production by targeting TRAF3 for autophagic degradation and disrupting TRAF3-TBK1 complex formation. Int J Biol Macromol. 2022 Oct 1;218:654-664.
Jia P#, Zhang WW#, Xiang Y, Lu X, Chen X, Pan H, Yi M, Jia K.The Capsid Protein of Nervous Necrosis Virus Antagonizes Host Type I IFN Production by a Dual Strategy to Negatively Regulate Retinoic Acid-Inducible Gene-I-like Receptor Pathways. J Immunol 209, 326-336 (2022).Jia, P., et al. The Capsid Protein of Nervous Necrosis Virus Antagonizes Host Type I IFN Production by a Dual Strategy to Negatively Regulate Retinoic Acid-Inducible Gene-I-like Receptor Pathways. J Immunol, 2022, 209, 326-336.
Zhang WW#; Lan Yao#; Xiaoqi Chen; Ming Li; Meisheng Yi; Kuntong Jia ; Functional characterization of myosin III light chain b of sea perch (Lateolabrax japonicus) in response to fish virus infection, Aquaculture, 2022, 550: 737840.
Zhang WW; Peng Jia; Xiaobing Lu; Xiaoqi Chen; Juehua Weng; Kuntong Jia; Meisheng Yi ; Capsid protein from red-spotted grouper nervous necrosis virus induces incomplete autophagy by in activating the HSP90ab1-AKT-MTOR pathway, Zoological Research, 2022, 43(1): 98-110.
Zhang WW; Xiaoqi Chen; Fangzhao Yu; Fengquan Li; Wangdong Li; Meisheng Yi; Kuntong Jia ; α-Lipoic acid exerts its antiviral effect against viral hemorrhagic septicemia virus (VHSV) by promoting upregulation of antiviral genes and suppressing VHSV-induced oxidative stress, Virol
ogica Sinica, 2021, 36: 1520-1531.
Zhang WW, Jia KT, Jia P, Xiang YX, Lu XB, Liu W & Yi MS. Marine medaka heat shock protein 90ab1 is a receptor for red-spotted grouper nervous necrosis virus and promotes virus internalization through clathrin-mediated endocytosis. PLOS Pathogens, 2020.16,e1008668.
Zhang WW, Jia P, Liu W, Jia KT & Yi MS. Screening for antiviral medaka haploid embryonic stem cells by genome wide mutagenesis. Marine Biotechnology, 2019, 21(2): 186-195.
Zhang WW, Li ZL, Xiang YX, Jia P, Liu W, Yi MS & Jia KT. Isolation and identification of a viral haemorrhagic septicaemia virus (VHSV) isolate from wild largemouth bass Micropterus salmoides in China. Journal of Fish Diseases, 2019, 42 (11): 1563-1572.
Zhang WW#, Jia P#, Liu W, Li YL, Yi MS & Jia KT. Functional characterization of tumor necrosis factor receptor-associated factor 3 of sea perch (Lateolabrax japonicas), in innate immune. Fish & Shellfish Immunology, 2018, 75: 1-7.
Zhang WW#, Li ZL#, Jia P, Liu W, Yi MS & Jia KT. Interferon regulatory factor 3 from sea perch (Lateolabrax japonicus) exerts antiviral function against nervous necrosis virus infection. Developmental & Comparative Immunology, 2018, 88: 200-205.
Zhang H, Zhang WW, Mo CY, Dong MD, Jia KT, Liu W, Yi MS. Production of functional sperm from in vitro-cultured premeiotic spermatogonia in a marine fish. Zool Res. 2022 Jul 18;43(4):537-551.
Xiang Y, Zhang WW, Jia P, Lu X, Liu W, Yi M, Jia K. E3 Ubiquitin Ligase RNF114 Inhibits Innate Immune Response to Red-Spotted Grouper Nervous Necrosis Virus Infection in Sea Perch by Targeting MAVS and TRAF3 to Mediate Their Degradation. J Immunol. 2021 Jan 1;206(1):77-88.
Liu W, Jin YL, Zhang WW, Xiang YX, Jia P, Yi MS & Jia KT. MiR-202-5p inhibits RIG-I-dependent innate immune responses to RGNNV infection by targeting TRIM25 to mediate RIG-I ubiquitination. Viruses, 2020, 12(3): 261-274.
Liu W, Xiang YX, Zhang WW, Jia P, Yi MS & Jia KT. Expression pattern, antiviral role and regulation analysis of interferon-stimulated gene 15 in black seabream, Acanthopagrus schlegelii. Fish & Shellfish Immunology, 2018, 82: 60-67.
Jin YL, Jia KT, Zhang WW, Xiang YX, Jia P, Liu W & Yi MS. Zebrafish TRIM25 promotes innate immune response to RGNNV infection by targeting 2CARD and RD regions of RIG-I for K63-linked ubiquitination. Frontiers in Immunology, 2019, 10: 2805-2817.
Jin YL, Liu W, Xiang YX, Zhang WW, Zhang H, Jia KT & Yi MS. Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42. Journal of Molecular Cell Biology, 2019, doi: 10.1093/jmcb/mjz103.
