招聘信息：有意申报本研究团队的特聘副研究员和博士后岗位的可电邮联系。另外，本团队独立招生硕士和博士研究生，欢迎报考！

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卢建国，新奥门31999“百人计划”急需人才，教授、博导、团队PI、院长助理、国家工程中心副主任。2012年在美国奥本大学获得博士学位，2017年入职新奥门31999新奥门31999，并组建了海洋生态基因组团队。现任国际地球生物基因组计划（EBP）委员、国际脊椎动物基因组计划（Vertebrate Genome Project）核心成员、剑桥大学Sanger研究院访问教授，主要从事海洋生物物种进化、重要经济性状的遗传基础、基因组选择育种的相关研究，及基因编辑育种技术的开发与应用。先后主持国家自然科学基金、国家外专局项目、省自然科学基金、中央级科研院所基本科研业务费等20余项科研项目，累积获得科研经费资助达1012万。在Nature Communication、Genome Biology、Nucleic Acid Research、Bioinformatics等知名期刊发表论文57篇，其中第一作者/通讯作者22篇，累计被引用2583次，H指数为28，合作出版英文专著1部，在世界知名Wiley-Blackwell出版社出版。目前担任Marine Biotechnology、BMC Genomics、Frontier in Genetics等SCI期刊的审稿专家。国家发明专利2项，实用新型专利6项。第八届中国国际“互联网+”大学生创新创业大赛金奖指导老师，排名第一，荣获2022年广东省自然资源科学技术二等奖1项，为第1完成人。

一、个人履历 Brief CV

• 2017.5-- 至今 新奥门31999“百人计划”，副教授/教授，博导
• 2012.8--2017.5 中国水产科学研究院黑龙江水产研究所，副研究员
• 2007.8--2012.8 美国奥本大学渔业系博士
• 2009.1--2011.5 美国奥本大学计算机硕士
• 2003.9--2006.7 南开大学分子生态学硕士

二、研究方向 Research Interests  

       海洋生态基因组；海洋生物基因组资源开发与利用；海洋生物组学大数据；种群遗传学和进化基因组学；鱼类性别差异机制；

三、项目课题 Programs

• 主持珠海市“金湾区农业农村和水务局黄立鱼种业体系研发能力建设项目”，480万，在研；
• 主持广州市科技攻关项目“基因组编辑技术在黄颡鱼单性育种中的应用”，100万，在研；
• 主持新奥门31999“基本业务费”，45万，结题；
• 主持国家自然基金项目“ 黄颡鱼性腺分化的转录组学证据”，结题；
• 主持省自然基金项目“黄颡鱼北方地理种群全基因组尺度SNP挖掘”结题；
• 主持农业部级重点项目一项“黄颡鱼雌雄生长差异的遗传机制”（项目编号：HSY201301）, 结题；
• 主持农业部级重点项目一项“哲罗鲑生殖生长调控分子机制研究”（项目编号：HSY201603）, 结题；
• 参加哈尔滨工业大学计算机学院生物信息学课题组，国家“863”计划课题 “微生物数字资源集成和信息服务关键技术研发”，结题；
• 参加国家“973”计划课题“重要养殖鱼类功能基因组和分子设计育种的基础研究”第五课题，课题名称“鱼类数量性状多基因聚合育种技术研究”；结题
• 参加国家“863”计划课题，课题名称：鲤生长等经济性状的主效基因发掘及育种潜力评估；结题
• 参加国家自然基金国合项目“雅罗鱼离子调控机制多样性及耐碱功能基因发掘”，2015.1-2017.12. 结题

四、荣誉与奖励 Honors

• 2017年获新奥门31999“百人计划”引进人才；
• 2013年入选中国水产科学研究院 “百人培育计划”；
• 2011年获美国奥本大学“H.S. Swingle”奖；
• 2011年获美国奥本大学“杰出国际研究生奖”；
• 2010年、2011年获“Plant and Animal Genome”国际会议奖；
• 2010年、2011年获美国“阿拉巴马州政府全额奖学金”

五、发表论文Publication

1. Lu J*, Huang P, Sun J, Liu J. DupScan: predicting and visualizing vertebrate genome duplication database. Nucleic Acids Res. 2022 Aug. IF=19.16
2. Fang W, Huang J, Li S, Lu J*. Identification of pigment genes (melanin, carotenoid and pteridine) associated with skin color variant in red tilapia using transcriptome analysis. Aquaculture. 2022. IF=4.242
3. Lu, J*., Gao, D., Sims, Y. et al. Chromosome-level Genome Assembly of Acanthopagrus latus Provides Insights into Salinity Stress Adaptation of Sparidae. Mar Biotechnol 24, 655–660 (2022). 
4. Genmei Lin, Junrou Huang, Kunwen Luo, Xianbiao Lin, Ming Su, Jianguo Lu*. Bacterial, archaeal, and fungal community structure and interrelationships of deep-sea shrimp intestine and the surrounding sediment. Environmental Research, 2022, 205: 112461. 
5. Gao, D., Huang, J., Lin, G, Lu J*. A time-course transcriptome analysis of gonads from yellow catfish (Pelteobagrus fulvidraco) reveals genes associated with gonad development. BMC Genomics 23 (Suppl 1), 409 (2022). 
6. Huang, J., Huang, P., Lu J*. et al. Gene expression profiles provide insights into the survival strategies in deep-sea mussel (Bathymodiolus platifrons) of different developmental stages. BMC Genomics 23 (Suppl 1), 311 (2022). 

7. Liu, H., Lin, G., Gao, D. et al Lu J*. Geographic Scale Influences the Interactivities Between Determinism and Stochasticity in the Assembly of Sedimentary Microbial Communities on the South China Sea Shelf. Microb Ecol 2022  

8. Lin G, Lu J*, Sun Z, Xie J, Huang J, Su M, Wu N*. Characterization of tissue-associated bacterial community of two Bathymodiolus species from the adjacent cold seep and hydrothermal vent environments. Science of the Total Environment. 2021, 796: 149046. 
9. Lin G, Huang J, Lu J, Su M, Hu B, Lin X*. Geochemical and microbial insights into vertical distributions of genetic potential of N-cycling processes in deep-sea sediments. Ecological Indicators. 2021, 125: 107461. 
10. Lin G, Li S, Huang J, Gao D, Lu J*. Hypoosmotic stress induced functional alternations of intestinal barrier integrity, inflammatory reactions, and neurotransmission along gut-brain axis in the yellowfin seabream (Acanthopagrus latus). Fish Physiology and Biochemistry. 2021.
11. Liu H, Prajapati V*, Prajapati S, Bais H, Lu J. Comparative genome analysis of Bacillus amyloliquefaciens focusing on phylogenomics, functional traits, and prevalence of antimicrobial and virulence genes. Frontiers in Genetics. 2021. 
12. Lin G, Gao D, Lu J*, Sun X. Transcriptome profiling insights the sexual dimorphism of gene expression patterns during gonad differentiation in the half-smooth tongue sole (Cynoglossus semilaevis). Marine Biotechnology. 2021, 23: 18-30.
13. Lu J*, Fang W, Huang J, Li S. The application of genome editing technology in fish. Marine Life Science & Technology. 2021, 3: 326-346.
14. Lin G, He Y, Lu J, Chen H, Feng J*. Seasonal variations in soil physicochemical properties and microbial community structure influenced by Spartina alterniflora invasion and Kandelia obovata restoration. Science of the Total Environment. 2021, 797: 149213. 1区Top, IF=7.963
15. Genmei Lin, Min Zheng, Dong Gao, Shizhu Li, Wenyu Fang, Jing Huang, Jingui Xie, Jingxiong Liu, Yijing Liu, Zhaohong Li, Jianguo Lu*. Hypoosmotic stress induced tissue-specific immune responses of yellowfin seabream (Acanthopagrus latus) revealed by transcriptomic analysis. Fish & Shellfish Immunology, 2020, 99: 473-482. Doi: 10.1016/j.fsi.2020.02.028.
16. Shizhu Li, Genmei Lin, Wenyu Fang, Peilin Huang, Dong Gao, Jing Huang, Jingui Xie, Jianguo Lu*. Gonadal transcriptome analysis of sex-related genes in the protandrous yellowfin seabream (Acanthopagrus latus). Frontiers in Genetics, 2020, 11: 709. Doi: 10.3389/fgene.2020.00709.
17. Genmei Lin, Min Zheng, Shizhu Li, Jingui Xie, Wenyu Fang, Dong Gao, Jing Huang, Jianguo Lu*. Response of gut microbiota and immune function to hypoosmotic stress in the yellowfin seabream (Acanthopagrus latus). Science of the Total Environment, 2020, 745: 140976. Doi: 10.1016/j.scitotenv.2020.140976.
18. Shizhu Li, Genmei Lin, Wenyu Fang, Dong Gao, Jing Huang, Jingui Xie, Jianguo Lu*. Identification and comparison of microRNAs in the gonad of the yellowfin seabream (Acanthopagrus latus). International Journal of Molecular Sciences, 2020, 21(16): 5690. Doi: 10.3390/ijms21165690.
19. Lin G#, Zheng M#, Gao D, Li S, Fang W, Huang J, Xie J, Liu J, Liu Y, Li Z, Lu J*. Hypoosmotic stress induced tissue-specific immune responses of yellowfin seabream (Acanthopagrus latus) revealed by transcriptomic analysis. Fish & Shellfish Immunology. 2020 April. 99:473-482.
20. Gao D, Zheng M, Lin G, Fang W, Huang J, Lu J*, Sun X. Construction of high-density genetic map and mapping of sex-related loci in the yellow catfish (Pelteobagrus fulyidraco). Marine Biotechnolgy.2020. DOI: 10.1007/s10126-019-09928-4.
21. Zheng M#, Lu J#, Lin G, Su H, Sun J, Luan T. Dysbiosis of gut microbiota by dietary exposure of three graphene-family materials in zebrafish (Danio rerio). Environ Pollut. 2019 Nov;254 (Pt A):112969.
22. Jiang L, Feng J, Ying R, Yin F, Pei S, Lu J, Cao Y, Guo J, Li Z. Individual and combined effects of ammonia-N and sulfide on the immune function and intestinal microbiota of Pacific white shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2019 Sep;92:230-240.
23. Zheng M, Lu J, Zhao D. Toxicity and Transcriptome Sequencing (RNA-seq) Analyses of Adult Zebrafish in Response to Exposure Carboxymethyl Cellulose Stabilized Iron Sulfide Nanoparticles. Sci Rep. 2018 May 24;8(1):8083.
24. Zheng M, Lu J, Zhao D. Effects of starch-coating of magnetite nanoparticles on cellular uptake, toxicity and gene expression profiles in adult zebrafish. Sci Total Environ. 2018 May 1;622-623:930-941.
25. J. Lu, E. Peatman, Q. Yang, S. Wang, Z. Hu, J. Reecy, H. Kucuktas, and Z. Liu. (2011) The catfish genome database cBARBEL: an informatic platform for genome biology of ictalurid catfish. Nucleic Acids Research. D815-21. （SCI  IF: 9.11）
26. J. Lu, E. Peatman, H. Tang, J. Lewis, and Z. Liu (2012) Profiling of gene duplication patterns of teleost genomes: Evidence for rapid lineage-specific genome expansion mediated by recent tandem duplications. BMC Genomics. 13:246. （SCI  IF: 3.98）
27. Lu J, Zheng M, Zheng J, et al. Transcriptomic Analyses Reveal Novel Genes with Sexually Dimorphic Expression in Yellow Catfish (Pelteobagrus fulvidraco) Brain[J]. Marine Biotechnology, 2015, 17(5): 613-623. （SCI  IF: 3.27）
28. Wang P, Zheng M, Liu J, Liu Y, Lu J*., Sun X. Sexually Dimorphic Gene Expression Associated with Growth and Reproduction of Tongue Sole (Cynoglossus semilaevis) Revealed by Brain Transcriptome Analysis. Int J Mol Sci. 2016 Aug 26;17(9). （SCI  IF: 3.252）
29. J. Lu, E. Peatman, W. Wang, Q. Yang, J. Abernathy, S. Wang, H. Kucuktas, and Z. Liu. (2011) Alternative splicing in teleost fish genomes: same-species and cross-species analysis and comparisons. Mol Genet Genomics. 283(6):531-9.（SCI IF: 2.635）
30. J. Lu, P. Luan, X. Zhang, S. Xue, L. Peng, S. Mahbooband, X Sun. (2014) Gonadal transcriptomic analysis of yellow catfish (Pelteobagrus fulvidraco): identification of sex-related genes and genetic markers. Physiol Genomics. 1;46(21):798-807. （SCI IF: 2.73）
31. Liu Y, Liu J, Lu J, Peng J, Juan L, Zhu X, Li B, Wang Y. Joint detection of copy number variations in parent-offspring trios. Bioinformatics. 2016 Apr 15;32(8):1130-7. （SCI IF: 5.766）
32. Tang, H., Zhang, X., Miao, C., Zhang, J., Ming, R., Schnable, J. C., & Lu, J. (2015). ALLMAPS: robust scaffold ordering based on multiple maps. Genome Biology, 16(1), 3. （SCI  IF: 10.81）
33. Liu Z, Liu S, Yao J, Bao L, Zhang J, Li Y, Jiang C, Sun L, Wang R, Zhang Y, Zhou T, Zeng Q, Fu Q, Gao S, Li N, Koren S, Jiang Y, Zimin A, Xu P, Phillippy AM, Geng X, Song L, Sun F, Li C, Wang X, Chen A, Jin Y, Yuan Z, Yang Y, Tan S, Peatman E, Lu J, Waldbieser GC. The channel catfish genome sequence provides insights into the evolution of scale formation in teleosts. Nat Commun. 2016 Jun 2;7:11757. （SCI IF: 11.329）
34. L. Peng, J. Lu, XW Sun. Mitochondrial DNA sequence of Lampetra morri. Mitochondrial DNA. 2014 Aug 12:1-2.
35. TB Huo, L. Peng, J. Lu*, ZF Jiang. Complete mitochondrial genome of the Lampetra japonica. Mitochondrial DNA. 2014 Aug 11:1-2.
36. TB Huo, L. Peng, ZF Jiang, J. Lu*. Complete mitochondrial genome of the Lampetra reissneri. Mitochondrial DNA. 2014 Aug 8:1-2.
37. PX Luan, JG Lu*,SQ Xue, XF Zhang, LN Peng, Sun XW. Mitochondrial DNA genome sequence of Ili marinka (Schizothorax pseudoaksaiensis). Mitochondrial DNA. 2014 Sep 10:1-2.
38. J. Abernathy, J. Lu, H. Liu, H. Kucuktas, and Z. Liu. (2009) Molecular characterization of complement factor I reveals constitutive expression in channel catfish. Fish and Shellfish Immunology. 27(3):529-34.
39. Y. Jiang, J. Lu, E. Peatman, H. Kucuktas, S. Liu, S. Wang, F. Sun, and Z. Liu. (2012) A Pilot Study for Channel Catfish Whole Genome Sequencing and de novo Assembly. BMC Genomics. 12(1):629.
40. LL. Wong, E. Peatman, J. Lu, H. Kucuktas, S. He, C. Zhou, U. Na-Nakorn, and Z. Liu. (2011) DNA barcoding of catfish: species authentication and phylogenetic assessment. PLoS One. 15; 6(3):e17812.
41. C. Li, Y. Zhang, R. Wang, J. Lu, S. Nandi, S. Mohanty, J. Terhune, J. Liu, and E. Peatman. (2012) RNA-seq Analysis of Mucosal Immune Responses Reveals Signatures of Intestinal Barrier Disruption and Pathogen Entry Following Edwardsiella ictaluri Infection in Channel Catfish, Ictalurus punctatus. Fish & Shellfish Immunology. doi: 10.1016/j.fsi.2012.02.004.
42. Z. Zhou, H. Liu, S, Liu, F. Sun, E. Peatman, H. Kucuktas, L. Kaltenboeck, T. Feng, H. Zhang, D. Niu, J. Lu, G. Waldbieser, and Z. Liu. (2012) Alternative complement pathway of channel catfish (Ictalurus punctatus): Molecular characterization, mapping and expression analysis of factors Bf/C2 and Df. Fish Shellfish Immunol. 32(1):186-95.
43. S. Liu, Z. Zhou, J. Lu, F. Sun, S. Wang, H. Liu, Y. Jiang, H. Kucuktas, L. Kaltenboeck, E. Peatman, and Z. Liu. (2011) Generation of genome-scale gene-associated SNPs in catfish for the construction of a high-density SNP array. BMC Genomics. 21:53.
44. D. Niu, E. Peatman, H. Liu, J. Lu, H. Kucuktas, S. Liu, F. Sun, H. Zhang, T. Feng, Z. Zhou, J. Terhune, G. Waldbieser, J. Li, and Z. Liu. (2011) Microfibrillar-associated protein 4 (MFAP4) genes in catfish play a novel role in innate immune responses. Dev Comp Immunol. 35(5): 568-79.
45. H. Liu, E. Peatman, W. Wang, J. Abernathy, S. Liu, H. Kucuktas, J. Lu, DH. Xu, P. Klesius, G. Waldbieser, and Z. Liu. Molecular responses of calreticulin genes to iron overload and bacterial challenge in channel catfish (Ictalurus punctatus). Dev Comp Immunol. 35(3): 267-72.
46. S. Wang, E. Peatman, J. Abernathy, G. Waldbieser, E. Lindquist, P. Richardson, S. Lucas, M. Wang, P. Li, J. Thimmapuram, L. Liu, D. Vullaganti, H. Kucuktas, C. Murdock, B.C. Small, M. Wilson, H. Liu, Y. Jiang, Y. Lee, F. Chen, J. Lu, W. Wang, P. Xu, B. Somridhivej, P. Baoprasertkul, J. Quilang, Z. Sha, B. Bao, Y. Wang, Q. Wang, T. Takano, S. Nandi, S. Liu, L. Wong, L. Kaltenboeck, S. Quiniou, E. Bengten, N. Miller, J. Trant, D. Rokhsar, Z. Liu and the catfish genome consortium. (2010) Assembly of 500,000 inter-specific catfish expressed sequence tags and large scale gene-associated marker development for whole genome association studies. Genome Biology 11(1):R8.