招生专业
个人详细介绍
学习和工作经历：
2005.9-2009.6，武汉大学生命科学学院，生命科学与技术基地班，获理学学士学位；
2009.9-2015.12，中国科学院水生生物研究所，遗传学专业，获理学博士学位。
2016.1-2020.5，新奥门31999新奥门31999特聘副研究员
2022.5-至今，新奥门31999新奥门31999特聘副教授
科研项目:
1、国家自然科学基金面上项目：斑马鱼生殖细胞高表达LncRNA—Lnc196调控生殖细胞发育的作用机制研究，58万元，主持，在研。
2、国家自然科学基金青年基金：黑鲷JAK-STAT信号通路在鱼类神经坏死病毒感染过程中的作用机制研究，20万元，主持，结题。
3、广东省基础与应用基础研究基金面上项目：中华乌塘鳢性腺分化基因的鉴定和功能研究，10万元，主持，在研。
4、淡水生态与生物技术国家重点实验室开放课题：基于单细胞转录组测序的斑马鱼PGC 的功能研究，8万元，主持，结题。
5、新奥门31999高校基本科研业务费青年教师培育项目：斑马鱼生殖细胞发育关键miRNA靶基因和功能研究，15万元，主持，结题。
6、国家重点研发计划课题：“重要养殖鱼类优良种质创制与生殖操作技术研究”课题 “重要养殖鱼类生殖干细胞诱导与移植技术”，66万元，任务负责人，在研。
7、国家重点研发计划（青年科学家项目）：精原干细胞体外诱导与基因编辑结合的鱼类精准性控技术，排名第二，在研。
8、国家自然科学基金面上项目：褪黑素促进中华乌塘鳢精原干细胞体外产生功能精子的机制研究，54万元，骨干，在研。
论文和专利:
1. Zhang, H.; Zhang, W.; Mo, C.; Dong, M.; Jia, K.; Liu, W.; Yi, M., Production of functional sperm from in vitro cultured premeiotic spermatogonia in a marine fish. Zoological Research 2022, 43, (4), 537.
2. Mo, C.; Li, W.; Jia, K.; Liu, W.; Yi, M., Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish. International Journal of Molecular Sciences 2021, 22, (21), 11962.
3. Dong, M.; Zhang, H.; Mo, C.; Li, W.; Zhang, W.; Jia, K.; Liu, W.; Yi, M., The CXC Chemokine Receptors in Four-Eyed Sleeper (Bostrychus sinensis) and Their Involvement in Responding to Skin Injury. International Journal of Molecular Sciences 2021, 22, (18).
4. Liu, W.; Zhang, H.; Xiang, Y.; Jia, K.; Luo, M.; Yi, M., A novel germline and somatic cell expression of two sexual differentiation genes, Dmrt1 and Foxl2 in marbled goby (Oxyeleotris marmorata). Aquaculture 2020, 516, 734619.
5. Liu, W.; Jin, Y.; Zhang, W.; Xiang, Y.; Jia, P.; Yi, M.; Jia, K., MiR-202-5p Inhibits RIG-I-Dependent Innate Immune Responses to RGNNV Infection by Targeting TRIM25 to Mediate RIG-I Ubiquitination. Viruses 2020, 12, (3), 261.
6. Liu, W.; Zhang, H.; Xiang, Y.; Jia, K.; Luo, M.; Yi, M., Molecular characterization of vasa homologue in marbled goby, Oxyeleotris marmorata: Transcription and localization analysis during gametogenesis and embryogenesis. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 2019, 229, 42-50.
7. Jin, Y.; Liu, W.; Xiang, Y.; Zhang, W.; Zhang, H.; Jia, K.; Yi, M., Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42. Journal of Molecular Cell Biology 2019.
8. Liu, W.; Xiang, Y.; Zhang, W.; Jia, P.; Yi, M.; Jia, K., Expression pattern, antiviral role and regulation analysis of interferon-stimulated gene 15 in black seabream, Acanthopagrus schlegelii. Fish & shellfish immunology 2018, 82, 60-67.
9. Zhang, J.; Liu, W.; Jin, Y.; Jia, P.; Jia, K.; Yi, M., MiR-202-5p is a novel germ plasm-specific microRNA in zebrafish. Scientific Reports 2017, 7, (1), 7055.
10. Xiang, Y.; Liu, W.; Jia, P.; Li, Y.; Jin, Y.; Chen, L.; Zhang, J.; Jia, K.; Yi, M., Molecular characterization and expression analysis of interferon-gamma in black seabream Acanthopagrus schlegelii. Fish & shellfish immunology 2017, 70, 140-148.
11. Li, S. Z.; Liu, W.; Li, Z.; Li, W. H.; Wang, Y.; Zhou, L.; Gui, J. F., greb1 regulates convergent extension movement and pituitary development in zebrafish. Gene 2017, 627, 176-187.
12. Li, S. Z.; Liu, W.; Li, Z.; Wang, Y.; Zhou, L.; Yi, M. S.; Gui, J. F., Molecular characterization and expression pattern of a germ cell marker gene dnd in gibel carp (Carassius gibelio). Gene 2016, 591, (1), 183-90.
13. Liu, W.; Li, S.-Z.; Li, Z.; Wang, Y.; Li, X.-Y.; Zhong, J.-X.; Zhang, X.-J.; Zhang, J.; Zhou, L.; Gui, J.-F., Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence. BMC genomics 2015, 16, (971), 1.
14. Zhang, W.; Jia, P.; Liu, W.; Jia, K.; Yi, M., Screening for Antiviral Medaka Haploid Embryonic Stem Cells by Genome Wide Mutagenesis. Mar Biotechnol 2019.
15. Xiang, Y.; Jia, P.; Liu, W.; Yi, M.; Jia, K., Comparative transcriptome analysis reveals the role of p53 signalling pathway during red-spotted grouper nervous necrosis virus infection in Lateolabrax japonicus brain cells. Journal of Fish Diseases 2019, 42, (4), 585-595.
16. Jin, Y.; Jia, K.; Zhang, W.; Xiang, Y.; Jia, P.; Liu, W.; Yi, M., Zebrafish TRIM25 Promotes Innate Immune Response to RGNNV Infection by Targeting 2CARD and RD Regions of RIG-I for K63-Linked Ubiquitination. Frontiers in Immunology 2019, 10, (2805).
17. Zhang, W.; Li, Z.; Jia, P.; Liu, W.; Yi, M.; Jia, K., Interferon regulatory factor 3 from sea perch (Lateolabrax japonicus) exerts antiviral function against nervous necrosis virus infection. Dev Comp Immunol 2018.
18. Zhang, W.; Jia, P.; Liu, W.; Li, Y.; Yi, M.; Jia, K., Functional characterization of tumor necrosis factor receptor-associated factor 3 of sea perch (Lateolabrax japonicas) in innate immune. Fish & shellfish immunology 2018, 75, 1-7.
19. Le, Y.; Jia, P.; Jin, Y.; Liu, W.; Jia, K.; Yi, M., The antiviral role of heat shock protein 27 against red spotted grouper nervous necrosis virus infection in sea perch. Fish & shellfish immunology 2017, 70, 185-194.
20. Jia, P.; Liu, W.; Chen, L.; Jin, Y.; Zhang, J.; Jia, K.; Yi, M., Identification of sea perch (Lateolabrax japonicus) ribonucleoprotein PTB-Binding 1 involved in antiviral immune response against RGNNV. Fish & shellfish immunology 2017, 60, 119-128.
21. Jia, K.; Yuan, Y.; Liu, W.; Liu, L.; Qin, Q.; Yi, M., Identification of Inhibitory Compounds Against Singapore Grouper Iridovirus Infection by Cell Viability-Based Screening Assay and Droplet Digital PCR. Mar Biotechnol 2017.
22. Zhang, J.; Sun, M.; Zhou, L.; Li, Z.; Liu, Z.; Li, X.Y.; Liu, X.L.; Liu, W.; Gui, J.F., Meiosis completion and various sperm responses lead to unisexual and sexual reproduction modes in one clone of polyploid Carassius gibelio. Sci. Rep. 2015, 5.
23. Wang, Y.; Li, W.H.; Li, Z.; Liu, W.; Zhou, L.; Gui, J.F., BMP and RA signaling cooperate to regulate Apolipoprotein C1 expression during embryonic development. Gene 2015, 554, (2), 196-204.
24. Li, X.Y.; Zhang, X.J.; Li, Z.; Hong, W.; Liu, W.; Zhang, J.; Gui, J.F., Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp. Molecular phylogenetics and evolution 2014, 78, (0), 96-104.
25. Jing, J.; Wu, J.; Liu, W.; Xiong, S.; Ma, W.; Zhang, J.; Wang, W.; Gui, J.-F.; Mei, J., Sex-biased miRNAs in gonad and their potential roles for testis development in yellow catfish. PloS one 2014, 9, (9), e107946.
26. 刘威，易梅生，张洪，张弯弯，李文静，莫承宇，一种精原细胞分离液及其在分离纯化云斑尖塘鳢精原细胞中的应用，2021
27. 刘威，易梅生，张洪，贾坤同，一种3D体外培养中华乌塘鳢精原细胞产生具有功能精子的方法，2022
28. 刘威，易梅生，张勇，汤明玥，董梦丹，张晋，李水生，一种黄鳍鲷精子的冷冻保存溶液及冷冻保存方法，2022
